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Ping-Shan Lai, Ph.D.

賴秉杉 教授

Professor of Department of Chemistry, National Chung Hsing University 

Phone : +886-4-22840411 ext 428

​

Fax : +886-4-22862547

pslai@email.nchu.edu.tw

Ping-Shan Lai, Ph.D.

Department of Chemistry, National Chung Hsing University, No.250, Kuo-Kuang Rd., Taichung 402, Taiwan

台中市國光路250號 化學館 4F 428

Education

  • B. S., National Chung Hsing University (2000.6)

  • Ph. D., National Taiwan University (2006.1). Advisor: Prof. Cheng-Yi Wang

  • Postdoctoral Fellow, National Chung Hsing University (2006.2-2006.7)

Teaching/Working Experiences

  • Professor                                                                           02/2015 – Present
    - Department of Chemistry, National Chung Hsing University, Taiwan

  • Vice Dean                                                                          02/2018 – 01/2019
    - College of Science, National Chung Hsing University, Taiwan

  • Division Chief, ISO17025 Lab director                            05/2014 – 07/2017

       - Center of Nanoscience and Nanotechnology, National Chung Hsing University,

         Taiwan

  • Division Chief                                                                    08/2016– 07/2019

       - Agricultural Products Approval and Certification Center, National Chung Hsing    

         University, Taiwan

  • Assistant Professor, Associate Professor                      02/2009 – 01/2015
    - Department of Chemistry, National Chung Hsing University, Taiwan

  • Project Assistant Professor                                             09/2006 – 01/2009           

​       - Department of Chemistry, National Chung Hsing University, Taiwan

  • Visiting Research                                                              05/2006 - 08/2006

​       - Department of Materials Engineering, The University of Tokyo, Japan

Awards

  • 2010  100學年度興大之光/The Pride of National Chung Hsing University

  • 2011  100學年度傑出青年教師/Outstanding Young Faculty Award, NCHU

  • 2012 Rising Suns in Asian (Controlled Release Society)

  • 2012「臺綜大年輕學者創新研究成果選拔」生科組優等獎 Young Scholar Research Award / Taiwan Comprehensive University System

  • 2013 第十屆國家新創獎/10th National Innovation Award

  • 2013 102 學年度傑出青年教師/Outstanding Young Faculty Award, NCHU

  • 2013 102 學年度興大之光/The Pride of National Chung Hsing University

  • 2013 中興大學研究績優獎/Outstanding Research Award / NCHU

  • 2015-2023 產學績優教師I/Academia-Industry Collaboration Award I, NCHU

Publications

  1. TY Chen+, NY Lin+, CH Wen, CA Lin, P Venkatesan, P Wijerathna, CY Lin and PS Lai*, Development of triamcinolone acetonide-hyaluronic acid conjugates with selective targeting and less osteoporosis effect for rheumatoid arthritis treatments, International Journal of Biological Macromolecules, 2023, 237, 124047. IF: 8.025

  2. CZ Li+, HM Chang+, WL Hsu, P. Venkatesan, MHC Lin and PS Lai*, Curcumin-loaded oil-free self-assembled micelles inhibit the influenza A virus activity and the solidification of curcumin-loaded micelles for pharmaceutical applications, Pharmaceutics, 2022, 14(11), 2422. IF: 6.525

  3. RK Lin, V Parthiban, CH Yeh, CM Chien, TS Lin, CC Lin, CC Lin* and PS Lai*, Effective topical treatments of innovative NNO-tridentate vanadium (IV) complexes-mediated photodynamic therapy in psoriasis-like mice model, Journal of Materials Chemistry B, 2022, 10, 4759 - 4770 (Front cover page) IF: 7.571

  4. L. Fernando, WT Chen, CW Lai, FY Ye, PS Lai, JJ Lin, K. Yasida, TT Song, JM Song, Biocompatibility and antimicrobial activity of copper(II) oxide hybridized with nano silicate platelets, Surface & Coating Technology, 2022, 435, 128253.

  5. Lin Wang+, SM Lai+, CZ Li, HP Yu, P. Venkatesan, PS Lai*, D-alpha-tocopheryl poly(ethylene glycol 1000) succinate-coated manganese-zinc ferrite nanomaterials for a dual-mode magnetic resonance imaging contrast agent and hyperthermia treatments, Pharmaceutics, 2022, 14(5), 1000. IF: 6.525

  6. H Lin, KC Cheng, JA  Lin, , LP Hsieh, CH Chou, YY Wang, PS Lai , PC Chu, Hsieh, CW, Pholiota nameko polysaccharides protect against ultraviolet a-Induced photoaging by regulating matrix metalloproteinases in human dermal fibroblasts, Antioxidant, 2022, 11(4), 739

  7. CA Lin, HM Ho, P Venkatesan, Ci Huang, YJ Cheng, YH Lin, HY Lin, TY Chen, MH Huang* and PS Lai*, Hyaluronic acid-glycine-cholesterol conjugate-based nanoemulsion as a potent vaccine adjuvant for T cell-mediated immunity, Pharmaceutics, 2021,13(10), 1569. IF: 6.525

  8. TY Chen+, CL Tseng+, CA Lin, HY Lin, P Venkatesan and PS Lai*, Effects of eye drops containing hyaluronic acid-nimesulide conjugates in a benzalkonium chloride-induced experimental dry eye rabbit model, Pharmaceutics, 2021,13(9), 1366. IF: 6.525

  9. MHC Lin, LC Chang, CY Chung, WC Huang, MH Lee, KT Chen, PS Lai, JT Yang, Internalization of etoposide using dendrimer nanospheres loaded with etoposide and protoporphyrin IX on a glioblastoma cell line, Pharmaceutics, 2021, 13(11), 1877. IF: 6.525

  10. YT Kao+, YT Chen+, HC Fan+, TC Tsai, SN Cheng, PS Lai, JK Chen and CM Chen*, Novel coagulation factor VIII gene therapy in a mouse model of hemophilia A by lipid-coated Fe3O4 nanoparticles, Biomedicines, 2021, 9(9), 1116. IF: 6.081

  11. SS Xu, H Zhang, CZ Li, PS Lai, GJ Wang, YS Chan, SG Cheng, XP Chen*, Cannabidiol promotes fin regeneration and reduces apoptosis in zebrafish embryos, Journal of Functional Foods, 2021, 86, 104694. IF: 4.451

  12. MHC Lin, PS Lai, LC Chang, WC Huang, MH Lee, KT Chen, CY Chung* and JT Yang*, Characterization and optimization of Chitosan-coated polybutylcyanoacrylate nanoparticles for the transfection-guided neural differentiation of mouse induced pluripotent stem cells, International Journal of Molecular Sciences, 2021, 22(16), 8741. IF: 5.924

  13. Y Li, YW Huang, Mi Wu, TY Wu, PS Lai, NN Sun, CY Saw, CW Li and CF Chau*, Enhanced resistance to amylolysis in rice kernels through interaction with chlorogenic acid, Processes, 2021, 9, 788. IF: 2.847

  14. P Venkatesan, PYM Yen, Y Uruma* and PS Lai, Designing synthetic glycosylated photosensitizers for photodynamic therapy, Bulletin of the Chemical Society of Japan, 2020, 93(8), 978-984. (Back Cover Page) IF: 5.488

  15. TJ Sung, YY Wang, KL Liu, CH Cou, PS Lai, CW Hsieh*, Pholiota nameko Polysaccharides promotes cell proliferation and migration and reduces ROS content in H2O2-induced L929 cells, Antioxidants, 2020, 9(1), 65. IF: 6.313

  16. HJ Chien, SM Lai, WC Wang, HY Lin, YM Juang, PS Lai* and CC Lai*, Preparation and comparison of Fe3O4@graphene oxide nanoclusters for analysis of glimepiride in urine by surface-assisted laser desorption/ionization time-of-flight mass spectrometry, Anal Bioanal Chem, 2020, 412(17), 4057-4065. IF: 4.157

  17. N Thirumalaivasan, P Venkatesan, PS Lai* and SP Wu*, In vitro and in vivo approach of hydrogen-sulfide-responsive drug release driven by azide-functionalized mesoporous silica nanoparticles, ACS Appl. Bio Mater, 2019, 2(9), 3886-3896

  18. WJ Syu, CC Huang, JK Hsiao, YC Lee, YT Huang and PS Lai*, Co-precipitation synthesis of near-infrared iron oxide nanocrystals on magnetically targeted imaging and photothermal cancer therapy via photoablative protein denature, Nanotheranostics, 2019, 3(3): 236-254. (Cover Page)

  19. P Venkatesan, N Thirumalivasan, HP Yu, PS Lai* and SP Wu*, Redox stimuli delivery vehicle based on transferrin-caped MSNPs for targeted drug delivery in cancer therapy, ACS Appl. Bio Mater.2019,24,1623-1633

  20. AT Rad+, CW Chen+, W Aresh+, Yan Xia, PS Lai*, MP Nieh* Combinational effects of active targeting, shape, and enhanced permeability and retention for cancer theranostic nanocarriers, ACS Appl. Mater. Interfaces, 2019, 11(11), 10505-10519 (+: equal contribution) IF: 9.229

  21. CH Chou, TJ Sung, YN Hu, HY Lu, LC Yang, KC Cheng, PS Lai, CW Hsieh*, Chemical analysis, moisture-preserving, and antioxidant activities of polysaccharides from Pholiota nameko by fractional precipitation, International Journal of Biological Macromolecules, 2019, 131, 1021-1031 IF:6.953

  22. CK Chang, WC Ko, YA Chen, YJ Chan, KC Cheng, PS Lai, CW Hsieh*, Evaluation of using high-pressure homogenization technology 1 in enhancing the aroma synthesis of sorghum spirits, LWT - Food Science and Technology, 2019, 105, 314-320. IF: 4.952

  23. JC Tsai, YA Chen, JT Wu, KC Cheng, PS Lai, KF Liu, YK Lin, YT Huang, CW Hsieh*, Extracts from fermented black garlic exhibit a hepatoprotective effect on acute hepatic injury, Molecules, 2019, 24, 1112. IF: 4.412

  24. MD Yang, CH Ho, S Ruta, R Chantrell, K Krycka, O Hovorka, FR Chen, PS Lai and CH Lai*, Magnetic interaction of multifunctional core-shell nanoparticles for highly effective theranostics, Advanced Materials, 2018, 30(50), e1802444. IF: 30.849

  25. MH Chang, YP Hsiao, CY Hsu and PS Lai*, Photo-crosslinked polymeric matrix with antimicrobial functions for excisional wound healing in mice, Nanomaterials, 2018, 8(10), 791. IF: 5.076

  26. YW Tai, YC Chiu, PT Wu, J Yu, YC Chin, SP Wu, YC Chunag, HC Hsieh, PS Lai, HP Yu and MY Liao*, Degradable NIR-PTT nanoagents with a potential Cu@Cu2O@polymer structure, ACS Applied Materials & Interfaces, 2018, 10(6), 5161-5174. IF: 9.229

  27. MH Chang, CL Pai, YC Chen, HP Yu, CY Hsu and PS Lai*, Enhanced antitumor effects of epidermal growth factor receptor targetable cetuximab-conjugated polymeric micelles for photodynamic therapy, Nanomaterials, 2018, 8(2), 121 IF: 5.076

  28. RK Lin, CI Chiu, CH Hsu, YJ Lai, P Venkatesan, PH Huang, PS Lai* and CC Lin*, Photocytotoxic copper (II) complexes with Schiff base scaffolds for photodynamic therapy, Chemistry - A European Journal, 2018, 24(16), 4111-4120. IF: 5.236

  29. CP Su, WJ Syu, CN Hsiao, PS Lai and CC Chen* Novel low-dose imaging technique for characterizing atomic structures through scanning transmission electron microscope, Physical Review Materials, 1 (2017), 033801. IF: 3.989

  30. CW Wang, CC Huang, PH Chou, YP Chang, S Wei, F. Peter Guengerich, YC Chou, SF Wang, PS Lai, P Souček and YF Ueng*, 7-Ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway, Oncotarget, 8 (2017), 66033-66050.  

  31. CW Chen+, WJ Syu+, TC Huang, YC Lee, JK Hsiao, KY Huang, HP Yu, MY Liao*, PS Lai* Encapsulation of Au/Fe3O4 nanoparticles into polymer nanoarchitecture with combined near infrared-triggering chemo-photothermal therapy based on intracellular secondary protein understanding, Journal of Materials Chemistry B, 5(29) (2017), 5774-5782. (+: equal contribution) IF: 6.331

  32. YS Jian, CW Chen, CA Lin, HP Yu, HY Lin, MY Liao, SH Wu, YF Lin* and PS Lai*, Hyaluronic acid–nimesulide conjugates as anticancer drugs against CD44-overexpressing HT-29 colorectal cancer in vitro and in vivo, International Journal of Nanomedicine, 12 (2017), 2315-2333. IF: 6.4

  33. A Goto, HC Yen, Y Anraku, S Fukushima, PS Lai, M Kato, A Kishimura*, K Kataoka*, Facile preparation of delivery platform of water-soluble low-molecular-weight drugs based on polyion complex vesicle (PICsome) encapsulating mesoporous silica nanoparticles, ACS Biomaterials Science & Engineering, 2017,3 (5)807-815 IF: 4.749

  34. SM Lai, YC Chiou, GF Chen, MY Liao, JTC Tzen and PS Lai*, Enhanced nuclear localization of photosensitizer using artificial oil bodies for photodynamic therapy, Smart Science, 2016, 4, 167-172.

  35. CL Pai, YC Chen, CY Hsu, HL Su, PS Lai*, Carbon nanotube-mediated photothermal disruption of endosomes/lysosomes reverses doxorubicin resistance in MCF-7/ADR cells, Journal of Biomedical Nanotechnology, 2016, 12, 619-629. IF: 4.099

  36. CH Lee+, PS Lai+, YP Lu, HY Chen, CY Chai, RK Tsai, KT Fang, MH Tsai, CY Hsu, CC Hung, DC Wu, HS Yu, CH Chang*, DP Tsai*, Real-time vascular imaging and photodynamic therapy efficacy with micelle-nanocarrier delivery of chlorin e6 to the microenvironment of melanoma, Journal of Dermatological Science, 2015 (80), 124-132 (+: equal contribution).

  37. CY Chang, SM Chen, HE Lu, SM Lai, PS Lai, PW Shen, PY Chen, CI Shen, HJ Harn, SZ Lin, SM Hwang, HL Su, N-butylidenephthalide attenuates Alzheimer’s disease-like cytopathy in down syndrome induced pluripotent stem cell-derived neurons, Scientific Reports, 2015, 5, 8744.

  38. SC Shen, CI Shen, H Lin, CJ Chen, CY Chang, SM Chen, HC Lee, PS Lai, HL Su, Susceptibility of human embryonic stem cell-derived neural cells to Japanese encephalitis virus infection, PLOS One, 2014, 9, e114990.

  39. CW Chen, CY Hsu, SM Lai, WJ Syu, TY Wang and PS Lai*, Metal nanobullets for multidrug resistant bacteria and biofilms, Advanced Drug Delivery Reviews, 2014, 78, 88-104. 

  40. CI Shen, HC Lee, YH Kao, CS Wu, PH Chen, SZ Lin, PS Lai, HL Su, EpCAM induction functionally links to the Wnt-enhanced cell proliferation in human keratinocytes, Cell Transplantation, 23(2014) 1031-1044. 

  41. SF Wang, YC Chou, N Mazumder, FJ Kao, LD Nagy, FP Guengerich, C Huang, HC Lee, PS Lai, YF Ueng, 7-Ketocholesterol induces P-glycoprotein through PI3K/mTORsignaling in hepatoma cells, Biochemical Pharmacology, 86 (2013) 548-560. 

  42. MY Liao, CH Wu, PS Lai, J Yu, HP Lin, TM Liu* and CC Huang*, Surface state mediated NIR two-photon fluorescence of iron oxides for nonlinear optical microscopy, Advanced Functional Materials, 23(16)(2013), 2044-2051. 

  43. CY Hsu, CW Chen, HP Yu, YF Lin and PS Lai*, Bioluminescence resonance energy transfer using luciferase-immobilized quantum dots for self-illuminated photodynamic therapy, Biomaterials, 34(4) (2013), 1204-1212. 

  44. CJ Ke, WL Chiang, ZX Liao, HL Chen, PS Lai, JS Sun* and HW Sung*, Real-time visualization of pH-responsive PLGA hollow particles containing a gas-generating agent targeted for acidic organelles for overcoming multi-drug resistance, Biomaterials, 34(1)(2013), 1-10.

  45. GF Chen, HP Tsai, PS Lai and MY Liao*, Functionalized Mn2+-doped zinc sulfide quantum dots as a metal ion sensor for industrial wastes, Sensors and Materials, 25(6) (2013) 437-442 

  46. CY Hsu, MP Nieh, PS Lai*, Facile self-assembly of porphyin-embedded polymeric vesicles for theranostic applications, Chemical Communications, 48 (75) (2012), 9343-9345. (Cover Page)

  47. SM Lai, JK Hsiao, HP Yu, CW Lu, CC Huang, MJ Shieh, PS Lai*, Polyethylene glycol-based biocompatable and highly stable superparamagnetic iron oxide nanoclusters for magnetic resonance imaging, Journal of Materials Chemistry, 22 (30) (2012) 15160-15167. 

  48. MY Liao, PS Lai, HP Yu, HP Lin* and CC Huang*, Innovative ligand-assisted synthesis of NIR-activated iron oxide for cancer theranostics, Chemical Communications, 48(43) (2012) 5319-5321.

  49. WJ Syu, HP Yu, CY Hsu, YC Rajan, YH Hsu, YC Chang, WY Hsieh, CH Wang, PS Lai*, Improved photodynamic cancer treatment by folate-conjugated polymeric micelles in KB xenografted animal model, Small, 8(13) (2012) 2060-2069. 

  50. HJ Fang, PS Lai, JY Chen, SCN Hsu, WD Peng, SW Ou, YC Lai, YJ Chen, H Chung, Y Chen, TC Huang, BS Wu and HY Chen*, ε-Caprolactone polymerization under air by the biocatalyst: Magnesium 2,6-di-tert-butyl-4-methylphenoxide, Journal of Polymer Science Part A: Polymer Chemistry, 2012 (50) 2697-2704. 

  51. SH Chiao, SH Lin, JI Shen, JW Liao, IJ Bau, JC Wei, LP Tseng, SH Hsu, PS Lai, SZ Lin, JJ Lin* and HL Su*, Efficacy and safety of nanohybrids comprising silver nanoparticles and silicate clay for controlling Salmonella infection, International Journal of Nanomedicine, 2012 (7) 2421–2432. 

  52. SM Lai, TY Tsai, CY Hsu, JL Tsai, MY Liao, PS Lai*, Bifunctional silica-coated superparamagnetic FePt nanoparticles for fluorescence/MR dual imaging, Journal of Nanomaterials, 2012 (2012), 631584. 

  53. TK Leung, CF Chan, PS Lai, CH Yang, CY Hsu, YS Lin* Inhibitory effects of far-infrared irradiation generated by ceramic material on murine melanoma cell growth, International Journal of Photoenergy, 2012 (2012), 646845. 

  54. HM Jan, MF Wei, CL Peng, SJ Lin, PS Lai*, MJ Shieh*, The use of polyethylenimine-DNA to topically deliver hTERT to promote hair growth, Gene Therapy, 19 (2012) 86-93 

  55. A Shiohara, S Prabakar, A Faramus, CY Hsu, PS Lai, PT Northcote and RD Tilley*, Size controlled synthesis, purification and cell studies with silicon quantum dots, Nanoscale, 3(8) (2011) 3364-3370 

  56. HL Lu, WJ Syu, N Nishiyama, K Kataoka and PS Lai*, Dendrimer phthalocyanine-encapsulated polymeric micelle-mediated photochemical internalization extends the efficacy of photodynamic therapy and overcome the drug-resistance in vivo, Journal of Controlled Release, 155 (3) 2011 458-464. 

  57. MJ Shieh+, CY Hsu+, LY Huang, HY Chen, FH Huang and PS Lai*, Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells, Journal of Controlled Release, 152(3) (2011) 418-425. (+: equal contribution) 

  58. CL Pai+, MJ Shieh+, PJ Lou, FH Huang, TW Wang and PS Lai*, Characterization of the uptake and intracellular trafficking of G4 polyamidoamine dendrimers, Australian Journal of Chemistry, 64(3) (2011) 302-308. (+: equal contribution) 

  59. FC Ding, PS Lai*, MJ Shieh, Nano-photosensitizer delivery, Chemistry, 68(3) (2010) 195-202. (Invited)

  60. PY Li, PS Lai*, WC Hung, WJ Syu, Poly(L-lactide)-vitamin E TPGS nanoparticles enhanced the cytotoxicity of doxorubicin in drug-resistant MCF-7 breast cancer cells, Biomacromolecules, 11(10) (2010) 2576-2582. 

  61. JR Lai, YW Chang, HC Yen, NY Yuan, MY Liao, CY Hsu, PS Lai*, Multifunctional doxorubicin/superparamagnetic iron oxide encapsulated Pluronic F127 micelles used for chemotherapy/magnetic resonance imaging, Journal of Applied Physics, 107 (2010) 09B318. 

  62. MJ Shieh, CL Peng, WL Cheung, CH Wang, CY Hsu, SJJ Wang and PS Lai*, Reduced skin photosensitivity with meta-tetra(hydroxyphenyl) chlorin-loaded micelles based on a poly (2-ethyl-2-oxazoline)-b-poly (D,L-lactide) diblock copolymer in vivo, Molecular Pharmaceutics, 7 (4) (2010) 1244-1253. 

  63. CL Peng, LY Yang, TY Luo, PS Lai, SJ Yang, WJ Lin, MJ Shieh*, Development of pH sensitive 2-(diisopropylamino)ethyl methacrylate based nanoparticles for photodynamic therapy, Nanotechnology, 21(15) (2010) 155103. 

  64. CL Peng, PS Lai, CC Chang, PJ Lou, MJ Shieh*, The synthesis and photodynamic properties of meso-substituted, cationic porphyrin derivatives in HeLa cells, Dyes and Pigments, 84 (2010) 140-147. 

  65. TY Luo*, IC Tang, YL Wu, KL Hsu, SW Liu, HC Kung, PS Lai and WJ Lin, Evaluating the potential of 188Re-SOCTA-Trastuzumab as a new radioimmunoagent for breast cancer treatment, Nuclear Medicine and Biology, 36 (2009) 81-88. 

  66. N Nishiyama, Y Nakagishi, Y Morimoto, PS Lai, K Miyazaki, K Urano, S Horie, M Kumagai, S Fukushima, WD Jang, M Kikuchi and K Kataoka*, Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine, Journal of Controlled Release, 133 (2009) 245-251. 

  67. CL Peng, PS Lai, FH Lin, SYH Wu and MJ Shieh*, Dual chemotherapy and photodynamic therapy in a HT-29 human colon cancer xenograft model using SN-38-loaded chlorin-core star block copolymer micelles, Biomaterials, 30 (2009) 3614-3625. 

  68. SJ Yang, MJ Shieh*, FH Lin, PJ Lou, CL Peng, MF Wei, CJ Yao, PS Lai, TH Young, Colorectal cancer cell detection by 5-aminolaevulinic acid-loaded chitosan nano-particles, Cancer Letters, 273 (2009) 210-220. 

  69. YH Hsin, CF Chen, S Huang, TS Shih, PS Lai, PJ Chueh*, The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells, Toxicology Letters, 179 (2008) 130-139. 

  70. CL Peng, MJ Shieh*, MH Tsai, CC Chang and PS Lai*, Self-assembled star-shaped chlorin-core poly(ε-caprolactone)-poly(ethylene-glycol) diblock copolymer micelles for dual chemo-photodynamic therapies, Biomaterials, 29 (2008) 3599-3608. 

  71. CL Peng, PS Lai and MJ Shieh*, Influence of substitutions on asymmetric porphyrin with regard to intracellular uptake, subcellular localization and phototoxicity in HeLa cells, Biomedical Engineering: Applications, Basis and Communications, 20 (2008) 9-17. 

  72. MJ Shieh, CL Peng, PJ Lou, CH Chiu, TY Tsai, CY Hsu, CY Yeh and PS Lai*, Non-toxic photo-triggered gene transfection by PAMAM-porphyrin conjugates, Journal of Controlled Release, 129 (2008) 200-206. 

  73. PS Lai, CL Pai, CL Peng, MJ Shieh*, K Berg and PJ Lou*, Enhanced cytotoxicity of saporin by polyamidoamine dendrimer conjugation and photochemical internalization, Journal of Biomedical Materials Research: Part A, 87A (2008) 147-155. 

  74. PS Lai, PJ Lou, CL Peng, CL Pai, WN Yen, MY Huang, TH Young and MJ Shieh*, Doxorubicin delivery by polyamidoamine dendrimer conjugation and photochemical internalization for cancer therapy, Journal of Controlled Release, 122 (2007) 39-46. 

  75. PJ Lou, PS Lai, MJ Shieh, AJ MacRobert, K Berg and SG Bown*, Reversal of doxorubicin resistance in breast cancer cells by photochemical internalisation, International Journal of Cancer, 119 (2006) 2692-2698. 

  76. PS Lai, MJ Shieh, CL Pai, CY Wang and TH Young*, A pH-sensitive EVAL membrane by blending with PAA, Journal of Membrane Science, 275 (2006) 89-96.

  77. PS Lai, TH Young, CY Wang and MJ Shieh*, In vitro release of hydrocortisone with glycine-immobilized EVAL membrane, Biomedical Engineering: Applications, Basis and Communications, 17 (2005) 86-90. 

  78. LP Cheng, KY Chang, PS Lai, and TH Young*, Study on the relationship between the ternary interaction parameter and the structure of water by the effect of aliphatic alcohols and phenol on the swelling behavior of poly(ethylene-co-vinyl alcohol) membrane in aqueous solution, European Polymer Journal, 40 (2004) 2531-2537.

  79. TH Young*, CT Tao and PS Lai, Phase behavior of Poly (ether imide) in mixtures of N-methyl-2-pyrrolidinone and methylene chloride, Polymer, 44 (2003) 1689-1695.

  80. MJ Shieh, PS Lai and TH Young*, 5-aminosalicylic acid permeability enhancement by a pH-sensitive EVAL membrane, Journal of Membrane Science, 204 (2002) 237-246.

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